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The oncogenic ADAMTS1–VCAN–EGFR cyclic axis drives anoikis resistance and invasion in renal cell carcinoma

Abstract Background Metastasis, the leading cause of renal cell carcinoma (RCC) mortality, involves cancer cells resisting anoikis and invading. Until now, the role of the matrix metalloproteinase (MMP)-related enzyme, A disintegrin and metalloprotease with thrombospondin motifs 1 (ADAMTS1), in RCC...

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Bibliografski detalji
Glavni autori: Yu-Ching Wen, Yung-Wei Lin, Kuo-Hao Ho, Yi-Chieh Yang, Feng-Ru Lai, Chih-Ying Chu, Ji-Qing Chen, Wei-Jiunn Lee, Ming-Hsien Chien
Format: Artigo
Jezik:Inglês
Izdano: BMC 2024-09-01
Serija:Cellular & Molecular Biology Letters
Teme:
Online pristup:https://doi.org/10.1186/s11658-024-00643-0
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