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Central sympathetic activation and arrhythmogenesis during acute myocardial infarction: modulating effects of endothelin-B receptors

Sympathetic activation during acute myocardial infarction is an important arrhythmogenic mechanism, but the role of central autonomic inputs and their modulating factors remain unclear. Using the in vivo rat-model, we examined the effects of clonidine, a centrally-acting sympatholytic agent, in the...

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Principais autores: Theofilos M Kolettis, Marianthi eKontonika, Eleonora eBarka, Evangelos P Daskalopoulos, Giannis G Baltogiannis, Christos eTourmousoglou, Apostolos ePapalois, Zenon S Kyriakides
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2015-02-01
Serier:Frontiers in Cardiovascular Medicine
Fag:
Ventricular arrhythmias
endothelin receptors
acute myocardial infarction
sympathetic activation
Acute left ventricular failure
Online adgang:http://journal.frontiersin.org/Journal/10.3389/fcvm.2015.00006/full
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