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Discovery of potential FGFR3 inhibitors via QSAR, pharmacophore modeling, virtual screening and molecular docking studies against bladder cancer

Abstract Background Fibroblast growth factor receptor 3 is known as a favorable aim in vast range of cancers, particularly in bladder cancer treatment. Pharmacophore and QSAR modeling approaches are broadly utilized for developing novel compounds for the determination of inhibitory activity versus t...

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Autors principals: Mahmoud Ganji, Shohreh Bakhshi, Alireza Shoari, Reza Ahangari Cohan
Format: Artigo
Idioma:Inglês
Publicat: BMC 2023-02-01
Col·lecció:Journal of Translational Medicine
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Accés en línia:https://doi.org/10.1186/s12967-023-03955-5
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