Fra2 Overexpression in Mice Leads to Non-allergic Asthma Development in an IL-13 Dependent Manner

Background: Asthma is a complex chronic inflammatory disease characterised by airway inflammation, remodelling and hyperresponsiveness (AHR). Members of the AP-1 transcription factor family play important roles in the activation of the immune system and the control of cellular responses; however, th...

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Detalhes bibliográficos

Principais autores:	Anna Gungl, Valentina Biasin, Jochen Wilhelm, Andrea Olschewski, Grazyna Kwapiszewska, Leigh M. Marsh
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2018-09-01
coleção:	Frontiers in Immunology
Assuntos:	extrinsic asthma AP-1 airway hyperresponsiveness Fra-2 mucus hypersecretion
Acesso em linha:	https://www.frontiersin.org/article/10.3389/fimmu.2018.02018/full
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