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Soluble P‐tau217 reflects amyloid and tau pathology and mediates the association of amyloid with tau

Abstract Alzheimer’s disease is characterized by β‐amyloid plaques and tau tangles. Plasma levels of phospho‐tau217 (P‐tau217) accurately differentiate Alzheimer’s disease dementia from other dementias, but it is unclear to what degree this reflects β‐amyloid plaque accumulation, tau tangle accumula...

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Autori principali: Niklas Mattsson‐Carlgren, Shorena Janelidze, Randall J Bateman, Ruben Smith, Erik Stomrud, Geidy E Serrano, Eric M Reiman, Sebastian Palmqvist, Jeffrey L Dage, Thomas G Beach, Oskar Hansson
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Nature 2021-05-01
Serie:EMBO Molecular Medicine
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Accesso online:https://doi.org/10.15252/emmm.202114022
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