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Activation of the Human Angiotensin-(1-12)-Chymase Pathway in Rats With Human Angiotensinogen Gene Transcripts

Angiotensin-(1-12) [Ang-(1-12)], an alternate substrate for tissue angiotensin II (Ang II) formation, underscores the importance of alternative renin-independent pathway(s) for the generation of angiotensins. Since renin enzymatic activity is species-specific, a transgenic model of hypertension due...

Whakaahuatanga katoa

I tiakina i:
Ngā kaituhi matua: Carlos M. Ferrario, Jessica VonCannon, Sarfaraz Ahmad, Kendra N. Wright, Drew J. Roberts, Hao Wang, Tomohisa Yamashita, Leanne Groban, Che Ping Cheng, James F. Collawn, Louis J. Dell'Italia, Jasmina Varagic
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Frontiers Media S.A. 2019-11-01
Rangatū:Frontiers in Cardiovascular Medicine
Ngā marau:
chymase
cardiac hypertrophy
hypertension
renin angiotensin system
transgenic rats
Urunga tuihono:https://www.frontiersin.org/article/10.3389/fcvm.2019.00163/full
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