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Prenatal nicotine exposure induces epigenetic alterations in the Notch signaling genes in the proximal colon in rats

Abstract Background Prenatal nicotine exposure (PNE) has been shown to significantly impact fetal development, leading to various pathologies in adulthood. Objectives In this study, we analyzed the epigenetic effects of PNE on the proximal colon. Results We show here that PNE decreases the length of...

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Autori principali: Ouzna Dali, Celine Heitz-Marchaland, Pierre-Yves Kernanec, Javier Carrion-Padilla, Baptiste Godin, Sergei Tevosian, Jasenka Zubcevic, Linda F. Hayward, Fatima Smagulova
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2025-09-01
Serie:BMC Genomics
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Accesso online:https://doi.org/10.1186/s12864-025-11960-9
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