Activation of a neural stem cell transcriptional program in parenchymal astrocytes

Adult neural stem cells, located in discrete brain regions, generate new neurons throughout life. These stem cells are specialized astrocytes, but astrocytes in other brain regions do not generate neurons under physiological conditions. After stroke, however, striatal astrocytes undergo neurogenesis...

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Hlavní autoři:	Jens P Magnusson, Margherita Zamboni, Giuseppe Santopolo, Jeff E Mold, Mauricio Barrientos-Somarribas, Carlos Talavera-Lopez, Björn Andersson, Jonas Frisén
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	eLife Sciences Publications Ltd 2020-08-01
Edice:	eLife
Témata:	neurogenesis astrocytes neural stem cells single-cell RNA sequencing regenerative medicine
On-line přístup:	https://elifesciences.org/articles/59733
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