CRISPR/Cas9-Mediated Disruption of the <i>lef8</i> and <i>lef9</i> to Inhibit Nucleopolyhedrovirus Replication in Silkworms

<i>Bombyx mori</i> nucleopolyhedrovirus (BmNPV) is a pathogen that causes severe disease in silkworms. In a previous study, we demonstrated that by using the CRISPR/Cas9 system to disrupt the BmNPV <i>ie-1</i> and <i>me53</i> genes, transgenic silkworms showed resistance to BmNPV infection. Here, we...

Description complète

Détails bibliographiques

Auteurs principaux:	Yujia Liu, Xiaoqian Zhang, Dongbin Chen, Dehong Yang, Chenxu Zhu, Linmeng Tang, Xu Yang, Yaohui Wang, Xingyu Luo, Manli Wang, Yongping Huang, Zhihong Hu, Zulian Liu
Format:	Artigo
Langue:	Inglês
Publié:	MDPI AG 2022-05-01
Collection:	Viruses
Sujets:	BmNPV CRISPR/Cas9 transgenic silkworm antiviral therapy
Accès en ligne:	https://www.mdpi.com/1999-4915/14/6/1119
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!