De novo biosynthesis of Asperosaponin VI in Saccharomyces cerevisiae

Asperosaponin VI (ASA VI), the primary bioactive triterpenoid saponin marker of Dipsacus asper Wall. (Chinese Pharmacopoeia 2020), possesses significant neuroprotective, anti-inflammatory, and osteogenic activities. However, its low natural abundance limits large-scale production. In this study, we...

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Autors principals:	Lin Hao, Guiru Dong, Tianzhen Sun, Jingyan Liu, Hui Wu, Fahui Li, Weiguo Song, Xiaozhou Luo, Jian Zhang, Yanan Qiao
Format:	Artigo
Idioma:	Inglês
Publicat:	KeAi Communications Co., Ltd. 2025-12-01
Col·lecció:	Synthetic and Systems Biotechnology
Matèries:	Asperosaponin VI Synthetic biology Saccharomyces cerevisiae UDP-Arabinose Glycosylation
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S2405805X25001188
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