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Leptin Regulation of Gonadotrope Gonadotropin-Releasing Hormone Receptors As a Metabolic Checkpoint and Gateway to Reproductive Competence

The adipokine leptin signals the body’s nutritional status to the brain, and particularly, the hypothalamus. However, leptin receptors (LEPRs) can be found all throughout the body and brain, including the pituitary. It is known that leptin is permissive for reproduction, and mice that cannot produce...

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Principais autores: Angela K. Odle, Noor Akhter, Mohsin M. Syed, Melody L. Allensworth-James, Helen Beneš, Andrea I. Melgar Castillo, Melanie C. MacNicol, Angus M. MacNicol, Gwen V. Childs
פורמט: Artigo
שפה:Inglês
יצא לאור: Frontiers Media S.A. 2018-01-01
סדרה:Frontiers in Endocrinology
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גישה מקוונת:http://journal.frontiersin.org/article/10.3389/fendo.2017.00367/full
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