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Efficacy of Phase I and Phase II <i>Coxiella burnetii</i> Bacterin Vaccines in a Pregnant Ewe Challenge Model

The bacterium <i>Coxiella burnetii</i> can cause the disease Q-fever in a wide range of animal hosts. Ruminants, including sheep, are thought to play a pivotal role in the transmission of <i>C. burnetii</i> to humans; however, the only existing livestock vaccine, namely, Coxevac<sup>®</sup> (Ceva An...

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Principais autores: Sarah E. Williams-Macdonald, Mairi Mitchell, David Frew, Javier Palarea-Albaladejo, David Ewing, William T. Golde, David Longbottom, Alasdair J. Nisbet, Morag Livingstone, Clare M. Hamilton, Stephen F. Fitzgerald, Søren Buus, Emil Bach, Annemieke Dinkla, Hendrik-Jan Roest, Ad P. Koets, Tom N. McNeilly
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2023-02-01
Serier:Vaccines
Fag:
Q-fever
<i>Coxiella burnetii</i>
vaccine
sheep
phase I
phase II
Online adgang:https://www.mdpi.com/2076-393X/11/3/511
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