tRF3008A suppresses the progression and metastasis of colorectal cancer by destabilizing FOXK1 in an AGO-dependent manner

Abstract Background tRNA-derived fragments (tRFs) have been shown to have critical regulatory roles in cancer biology. However, the contributions of tRFs to colorectal cancer (CRC) remain largely unknown. Methods tRF3008A (a tRFRNA derived from tRNAVal) was identified by RNA sequencing and validated...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Ying Han, Yinghui Peng, Shanshan Liu, Xinwen Wang, Changjing Cai, Cao Guo, Yihong Chen, Le Gao, Qiaoqiao Huang, Min He, Edward Shen, Jie Long, Jian Yu, Hong Shen, Shan Zeng
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2022-01-01
coleção:	Journal of Experimental & Clinical Cancer Research
Assuntos:	tRNA-derived fragments (tRFs) tRF3008A FOXK1 AGO Colorectal cancer
Acesso em linha:	https://doi.org/10.1186/s13046-021-02190-4
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!