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Association of endothelial and glycocalyx injury biomarkers with fluid administration, development of acute kidney injury, and 90-day mortality: data from the FINNAKI observational study

Abstract Background Injury to endothelium and glycocalyx predisposes to vascular leak, which may subsequently lead to increased fluid requirements and worse outcomes. In this post hoc study of the prospective multicenter observational Finnish Acute Kidney Injury (FINNAKI) cohort study conducted in 1...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Nina Inkinen, Ville Pettilä, Päivi Lakkisto, Anne Kuitunen, Sakari Jukarainen, Stepani Bendel, Outi Inkinen, Tero Ala-Kokko, Suvi T. Vaara, the FINNAKI Study Group
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2019-09-01
Schriftenreihe:Annals of Intensive Care
Schlagworte:
Biomarker
Glycocalyx
Sepsis
Fluid balance
Fluid resuscitation
Soluble thrombomodulin
Online-Zugang:http://link.springer.com/article/10.1186/s13613-019-0575-y
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