High-Throughput Virtual Screening of Compounds with Electrophilic Fragments for New Potential Covalent Inhibitors of Bacterial Proteins

The search for new antibacterial drugs has continued to be an urgent matter. One of the approaches is the development of covalent inhibitors using biochemoinformatics at the initial stages. In this work, structures of a few plant-derived substances with electrophilic unsaturated carbonyl and structu...

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מידע ביבליוגרפי

Principais autores:	Polina Yakovets, Viktoryia Staravoitava, Yaroslav Faletrov, Vladimir Shkumatov
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	MDPI AG 2022-11-01
סדרה:	Chemistry Proceedings
נושאים:	docking antibacterial drugs covalent inhibitors bacterial proteins fragment-based drug discovery
גישה מקוונת:	https://www.mdpi.com/2673-4583/12/1/87
תגים:	הוספת תג אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!