Aspartame exposure impairs bone formation in zebrafish larvae through ferroptosis-associated redox dysregulation, accompanied by an NRF2-related antioxidant response

Aspartame (ASP), a widely used artificial sweetener, has been reported to exert potential neurotoxic, hepatotoxic, nephrotoxic, and genotoxic effects; however, its impact on bone formation and skeletal homeostasis remains poorly understood. In this study, we investigated the effects of ASP exposure...

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Egile Nagusiak:	Chang-Yu Yan, Xiao-Yuan Gu, Jiang-Hao Mao, Ao-Yu Mei, Jie Sun, Hiroshi Kurihara, Yi-Fang Li, Rong-Rong He, Ping-Hua Sun, Wei-Xi Li
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Elsevier 2026-07-01
Saila:	Journal of Agriculture and Food Research
Gaiak:	Aspartame Ferroptosis Bone formation Skeletal toxicity NRF2 Zebrafish
Sarrera elektronikoa:	http://www.sciencedirect.com/science/article/pii/S2666154326005041
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