Differential Involvement of ACKR3 C-Tail in β-Arrestin Recruitment, Trafficking and Internalization

<b>Background</b>: The atypical chemokine receptor 3 (ACKR3) belongs to the superfamily of G protein-coupled receptors (GPCRs). Unlike classical GPCRs, this receptor does not activate G proteins in most cell types but recruits β-arrestins upon activation. ACKR3 plays an important role in cancer and...

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Principais autores:	Aurélien Zarca, Claudia Perez, Jelle van den Bor, Jan Paul Bebelman, Joyce Heuninck, Rianna J. F. de Jonker, Thierry Durroux, Henry F. Vischer, Marco Siderius, Martine J. Smit
Formato:	Artigo
Idioma:	Inglês
Publicado:	MDPI AG 2021-03-01
Series:	Cells
Assuntos:	GPCR ACKR3 chemokine receptor protein phosphorylation β-arrestins bioluminescence energy transfer (BRET)
Acceso en liña:	https://www.mdpi.com/2073-4409/10/3/618
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