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Aminoquinolones and Their Benzoquinone Dimer Hybrids as Modulators of Prion Protein Conversion

Prion Diseases or Transmissible Spongiform Encephalopathies are neurodegenerative conditions associated with a long incubation period and progressive clinical evolution, leading to death. Their pathogenesis is characterized by conformational changes of the cellular prion protein—PrP<sup>C</sup>—in i...

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Principais autores: Amanda Rodrigues Pinto Costa, Marcelly Muxfeldt, Fernanda da Costa Santos Boechat, Maria Cecília Bastos Vieira de Souza, Jerson Lima Silva, Marcela Cristina de Moraes, Luciana Pereira Rangel, Tuane Cristine Ramos Gonçalves Vieira, Pedro Netto Batalha
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2022-11-01
Serier:Molecules
Fag:
quinone
oxoquinoline
quinolone
scrapie
prion
Online adgang:https://www.mdpi.com/1420-3049/27/22/7935
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