Synergistic antitumor effects of circularly permuted TRAIL with doxorubicin in triple-negative breast cancer

Circularly permuted TRAIL (CPT), a novel recombinant TRAIL mutant, is a potent antitumor agent. However, its efficacy in triple-negative breast cancer (TNBC) remains unclear. Treatment with CPT alone and in combination with doxorubicin (Dox) is explored for its effects on the proliferation and apopt...

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Detalhes bibliográficos

Principais autores:	Liu Jia, Zhu Tienian, Liu Jiankun, Cui Yujie, Yang Shifang, Zhao Ruijing
Formato:	Artigo
Idioma:	Inglês
Publicado em:	China Science Publishing & Media Ltd. 2023-08-01
Colecção:	Acta Biochimica et Biophysica Sinica
Assuntos:	apoptosis TRAIL doxorubicin death receptor triple-negative breast cancer
Acesso em linha:	https://www.sciengine.com/doi/10.3724/abbs.2023160
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