A phase I thorough QT/QTc study evaluating therapeutic and supratherapeutic doses of avacopan in healthy participants
Abstract This phase I thorough QTc, double‐blind, randomized, placebo‐ and positive‐controlled, parallel group, multiple‐dose study evaluated avacopan's effect on cardiac repolarization using concentration‐QTc (C‐QTc) as the primary analysis. Avacopan 30 mg b.i.d. (therapeutic dose) was administered...
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| Principais autores: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Wiley
2024-07-01
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| Colecção: | Clinical and Translational Science |
| Acesso em linha: | https://doi.org/10.1111/cts.13878 |
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