The exposure of autoantigens by microparticles underlies the formation of potent inflammatory components: the microparticle‐associated immune complexes

Abstract Immunoglobulins, antigens and complement can assemble to form immune complexes (IC). ICs can be detrimental as they propagate inflammation in autoimmune diseases. Like ICs, submicron extracellular vesicles termed microparticles (MP) are present in the synovial fluid from patients affected w...

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Detalhes bibliográficos

Principais autores:	Nathalie Cloutier, Sisareuth Tan, Luc H. Boudreau, Catriona Cramb, Roopashree Subbaiah, Lauren Lahey, Alexandra Albert, Ruslan Shnayder, Reuben Gobezie, Peter A. Nigrovic, Richard W. Farndale, William H. Robinson, Alain Brisson, David M. Lee, Eric Boilard
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Springer Nature 2012-12-01
coleção:	EMBO Molecular Medicine
Assuntos:	arthritis autoantigens immune complexes microparticles platelets
Acesso em linha:	https://doi.org/10.1002/emmm.201201846
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