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Evaluation of Myocilin Variant Protein Structures Modeled by AlphaFold2

Deep neural network-based programs can be applied to protein structure modeling by inputting amino acid sequences. Here, we aimed to evaluate the AlphaFold2-modeled myocilin wild-type and variant protein structures and compare to the experimentally determined protein structures. Molecular dynamic an...

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Furkejuvvon:
Váldodahkkit: Tsz Kin Ng, Jie Ji, Qingping Liu, Yao Yao, Wen-Ying Wang, Yingjie Cao, Chong-Bo Chen, Jian-Wei Lin, Geng Dong, Ling-Ping Cen, Chukai Huang, Mingzhi Zhang
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: MDPI AG 2023-12-01
Ráidu:Biomolecules
Fáttát:
AlphaFold2
myocilin
variants
protein structure
molecular simulation
Liŋkkat:https://www.mdpi.com/2218-273X/14/1/14
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