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Effect of amlodipine, lisinopril and allopurinol on acetaminophen-induced hepatotoxicity in rats

Background: Exposure to chemotherapeutic agents such as acetaminophen may lead to serious liver injury. Calcium deregulation, angiotensin II production and xanthine oxidase activity are suggested to play mechanistic roles in such injury. Objective: This study evaluates the possible protective effect...

Ausführliche Beschreibung

Gespeichert in:
Bibliografische Detailangaben
Hauptverfasser: Nesreen E.M. Mohammed, Basim A.S. Messiha, Ali A. Abo-Saif
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer 2016-11-01
Schriftenreihe:Saudi Pharmaceutical Journal
Schlagworte:
Online-Zugang:http://www.sciencedirect.com/science/article/pii/S1319016415001000
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