A Novel, Comprehensive A129 Mouse Model for Investigating Dengue Vaccines and Evaluating Pathogenesis

In search of a mouse model for use in evaluating dengue vaccines, we assessed A129 mice that lacked IFN-α/β receptors, rendering them susceptible to dengue virus (DENV) infection. To our knowledge, no reports have evaluated dengue vaccine efficiency using A129 mice. A129 mice were given a single int...

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Principais autores:	Mya Myat Ngwe Tun, Khine Mya Nwe, Jean Claude Balingit, Yuki Takamatsu, Shingo Inoue, Basu Dev Pandey, Takeshi Urano, Michinori Kohara, Kyoko Tsukiyama-Kohara, Kouichi Morita
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2023-12-01
coleção:	Vaccines
Assuntos:	A129 mouse Dengvaxia vaccine dengue virus neutralization antibody viral loads
Acesso em linha:	https://www.mdpi.com/2076-393X/11/12/1857
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