Development of a Potent and Protective Germline-Like Antibody Lineage Against Zika Virus in a Convalescent Human

Zika virus (ZIKV) specific neutralizing antibodies hold great promise for antibody-based interventions and vaccine design against ZIKV infection. However, their development in infected patients remains unclear. Here, we applied next-generation sequencing (NGS) to probe the dynamic development of a p...

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Principais autores:	Fei Gao, Xiaohe Lin, Linling He, Ruoke Wang, Han Wang, Xuanling Shi, Fuchun Zhang, Chibiao Yin, Linqi Zhang, Jiang Zhu, Lei Yu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2019-10-01
Colecção:	Frontiers in Immunology
Assuntos:	Zika virus infection Guillain–Barré syndrome microcephaly neutralizing antibody antibody repertoire next-generation sequencing
Acesso em linha:	https://www.frontiersin.org/article/10.3389/fimmu.2019.02424/full
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