Oxidative Stress Levels and DNA Repair Kinetics in Senescent Primary Human Fibroblasts Exposed to Chronic Low Dose Rate of Ionizing Radiation

Background: Exposure to low dose rate (LDR) radiation may accelerate aging processes. Previously, we identified numerous LDR-induced pathways involved in oxidative stress (OS) and antioxidant systems, suggesting that these pathways protect against premature senescence (PS). This study aimed to inves...

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Detalhes bibliográficos

Principais autores:	Traimate Sangsuwan, Ali Pour Khavari, Evelina Blomberg, Tajanena Romell, Paulo Roberto D'auria Vieira De Godoy, Mats Harms-Ringdahl, Siamak Haghdoost
Formato:	Artigo
Idioma:	Inglês
Publicado em:	IMR Press 2023-11-01
Colecção:	Frontiers in Bioscience-Landmark
Assuntos:	radiation chronic radiation low dose rate premature senescence replicative senescence dna repair radiotherapy oxidative stress hmth1 telomere length extracellular 8-oxo-dg
Acesso em linha:	https://www.imrpress.com/journal/FBL/28/11/10.31083/j.fbl2811296
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