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Comprehensive Insights into Obesity and Type 2 Diabetes from Protein Network, Canonical Pathway, Phosphorylation and Antimicrobial Peptide Signatures of Human Serum

Background: Obesity is a major risk factor for type 2 diabetes (T2D); however, the molecular links between these conditions are not fully understood. Methods: We performed an integrative serum proteomics study on samples from 134 individuals (healthy controls, patients with obesity and/or T2D) using...

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Autori principali: Petra Magdolna Bertalan, Erdenetsetseg Nokhoijav, Ádám Pap, George C. Neagu, Miklós Káplár, Zsuzsanna Darula, Gergő Kalló, Laszlo Prokai, Éva Csősz
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2025-12-01
Serie:Proteomes
Soggetti:
obesity
type 2 diabetes
mass spectrometry
phosphoproteomics
network analysis
AMP
Accesso online:https://www.mdpi.com/2227-7382/13/4/67
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