Diversity and bias through receptor-receptor interactions in GPCR heteroreceptor complexes. Focus on examples from dopamine D2 receptor heteromerization

Allosteric receptor-receptor interactions in GPCR heteromers appeared to introduce an intermolecular allosteric mechanism contributing to the diversity and bias in the protomers. Examples of dopamine D2R heteromerization are given to show how such allosteric mechanisms significantly change the recep...

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Bibliografske podrobnosti

Principais autores:	Kjell eFuxe, Alexander O Tarakanov, Wilber eRomero-Fernández, Luca eFerraro, Sergio eTanganelli, Małgorzata eFilip, Luigi Francesco Agnati, Pere eGarriga, Zaida eDiaz Cabiale, Dasiel Oscar Borroto-Escuela
Format:	Artigo
Jezik:	Inglês
Izdano:	Frontiers Media S.A. 2014-05-01
Serija:	Frontiers in Endocrinology
Teme:	Oligomerization receptor-receptor interactions Dopamine receptor d G protein coupled receptor heterodimerization
Online dostop:	http://journal.frontiersin.org/Journal/10.3389/fendo.2014.00071/full
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