Recent development of mitochondrial metabolism and dysfunction in osteoarthritis

Osteoarthritis is a degenerative joint disorder characterized by cartilage degradation, synovial inflammation, and altered subchondral bone structure. Recent insights have identified mitochondrial dysfunction as a pivotal factor in OA pathogenesis, contributing to chondrocyte apoptosis, oxidative st...

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Detalhes bibliográficos

Principais autores:	Pengchao Guo, Ahmad Alhaskawi, Safwat Adel Abdo Moqbel, Zhijun Pan
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2025-02-01
Colecção:	Frontiers in Pharmacology
Assuntos:	osteoarthritis cartilage degradation mitochondrial dysfunction mitochondrial metabolism inflammation
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fphar.2025.1538662/full
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