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Hallmarks of frailty and osteosarcopenia in prematurely aged PolgA(D257A/D257A) mice

Abstract Background Frailty is a geriatric syndrome characterized by increased susceptibility to adverse health outcomes. One major determinant thereof is the gradual weakening of the musculoskeletal system and the associated osteosarcopenia. To improve our understanding of the underlying pathophysi...

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Bibliographic Details
Main Authors: Ariane C. Scheuren, Gommaar D'Hulst, Gisela A. Kuhn, Evi Masschelein, Esther Wehrle, Katrien De Bock, Ralph Müller
Format: Artigo
Language:Inglês
Published: Wiley 2020-08-01
Series:Journal of Cachexia, Sarcopenia and Muscle
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Online Access:https://doi.org/10.1002/jcsm.12588
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