Neuregulin 1 improves cognitive deficits and neuropathology in an Alzheimer’s disease model

Abstract Several lines of evidence suggest that neuregulin 1 (NRG1) signaling may influence cognitive function and neuropathology in Alzheimer’s disease (AD). To test this possibility, full-length type I or type III NRG1 was overexpressed via lentiviral vectors in the hippocampus of line 41 AD mouse...

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Autors principals:	Jiqing Xu, Fred de Winter, Catherine Farrokhi, Edward Rockenstein, Michael Mante, Anthony Adame, Jonathan Cook, Xin Jin, Eliezer Masliah, Kuo-Fen Lee
Format:	Artigo
Idioma:	Inglês
Publicat:	Nature Portfolio 2016-08-01
Col·lecció:	Scientific Reports
Accés en línia:	https://doi.org/10.1038/srep31692
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