In‐Depth Cell‐Type‐Specific Proteome Landscape of the Brain from Human Amyloid‐β Overexpression Mouse Model

Abstract Amyloid‐β (Aβ) plays a crucial role in Alzheimer's disease pathogenesis. Understanding how Aβ overexpression alters the proteome of individual brain cell types is essential but challenging due to the nature of brain tissue, which contains intermingled various cell types. The current methods...

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Detalhes bibliográficos

Principais autores:	Taekyung Ryu, Seok‐Young Kim, Thujitha Thuraisamy, Jisu Shin, Yura Jang, Tae‐In Kam, Chan Hyun Na
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2025-05-01
coleção:	Advanced Science
Assuntos:	biotin‐tyramides brains cell‐type‐specific proteomes iCAB biotinylation immunohistochemistry
Acesso em linha:	https://doi.org/10.1002/advs.202409318
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