Systemic knockout of Tmem175 results in aberrant differentiation but no effect on hematopoietic reconstitution

Lysosomes play crucial roles in regulating cell metabolism, and K+ channels are critical for controlling various aspects of lysosomal function. Additionally, lysosomal activity is essential for maintaining the quiescence of hematopoietic stem cells (HSCs) under both steady-state and stress condition...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Jingjing Su, Yue Wang, Jiyuan Yao, Leimin Sun, Chunzhen Zhao, Leiming Liu, Lingling Zhang
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Elsevier 2024-09-01
Цуврал:	Stem Cell Research
Нөхцлүүд:	Tmem175 Hematopoietic stem cell Bone marrow transplantation Lysosome Potassium channel
Онлайн хандалт:	http://www.sciencedirect.com/science/article/pii/S1873506124001673
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!