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Mechanistic and therapeutic dimensions of DcR3-mediated immunomodulation in sepsis

Sepsis is a life-threatening syndrome characterized by dysregulated host-immune responses, progressing through hyperinflammatory and immunosuppressive stages. Decoy receptor 3 (DcR3), a soluble member of the TNF receptor superfamily, serves as an immunomodulator in sepsis. Beyond neutralizing FasL,...

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Bibliografiske detaljer
Principais autores: Bilal Abbas, Xinrui Lin, Chen Xu, Qi Chen, Jingqian Su
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2026-01-01
Serier:Frontiers in Immunology
Fag:
Online adgang:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1750066/full
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