Curated CYP450 Interaction Dataset: Covering the Majority of Phase I Drug Metabolism
Abstract We collected and organized a detailed dataset encompassing both substrates and non-substrates for six principal cytochrome P450 (CYP450) isozymes, responsible for 90% of Phase I drug metabolism in humans. These isozymes, specifically CYP1A2, CYP2C9, CYP2C19, CYP2D6, CYP2E1, and CYP3A4, play...
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| Principais autores: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Portfolio
2025-08-01
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| coleção: | Scientific Data |
| Acesso em linha: | https://doi.org/10.1038/s41597-025-05753-8 |
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