HIV-1 Tat-induced disruption of epithelial junctions and epithelial-mesenchymal transition of oral and genital epithelial cells lead to increased invasiveness of neoplastic cells and the spread of herpes simplex virus and cytomegalovirus
Human immunodeficiency virus (HIV-1) transactivator Tat is a unique multi-functional viral protein secreted by infected cells. Although its primary function is to promote HIV-1 transcription, secreted Tat interacts with neighboring cells and induces numerous disease-associated pathological changes....
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| Format: | Artigo |
| Idioma: | Inglês |
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Frontiers Media S.A.
2025-02-01
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| Col·lecció: | Frontiers in Immunology |
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| Accés en línia: | https://www.frontiersin.org/articles/10.3389/fimmu.2025.1541532/full |
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