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The transcriptional response in human umbilical vein endothelial cells exposed to insulin: a dynamic gene expression approach.

BACKGROUND: In diabetes chronic hyperinsulinemia contributes to the instability of the atherosclerotic plaque and stimulates cellular proliferation through the activation of the MAP kinases, which in turn regulate cellular proliferation. However, it is not known whether insulin itself could increase...

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Bibliografiske detaljer
Principais autores: Barbara Di Camillo, Tiziana Sanavia, Elisabetta Iori, Vincenzo Bronte, Enrica Roncaglia, Alberto Maran, Angelo Avogaro, Gianna Toffolo, Claudio Cobelli
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2010-01-01
Serier:PLoS ONE
Online adgang:http://europepmc.org/articles/PMC3008714?pdf=render
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