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Extracellular Vesicles from Regenerating Skeletal Muscle Mitigate Muscle Atrophy in an Amyotrophic Lateral Sclerosis Mouse Model

Amyotrophic lateral sclerosis (ALS) is a devastating neuromuscular disease characterized by progressive motor neuron degeneration and muscle atrophy, with no effective treatments available. Chronic inflammation, which impairs muscle regeneration and promotes proteolysis, is a key contributor to ALS-...

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Principais autores: Jinghui Gao, Aria Sikal, Rachel Hankin, Yaochao Zheng, Elijah Sterling, Kenny Chan, Yao Yao
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2025-03-01
Serier:Cells
Fag:
amyotrophic lateral sclerosis
regenerating skeletal muscle
extracellular vesicles
muscle atrophy
Online adgang:https://www.mdpi.com/2073-4409/14/6/464
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