IFN-β Plays Both Pro- and Anti-inflammatory Roles in the Rat Cardiac Fibroblast Through Differential STAT Protein Activation

Cardiac fibroblasts (CFs) contribute to theinflammatory response to tissue damage, secreting both pro- and anti-inflammatory cytokines and chemokines. Interferon beta (IFN-β) induces the phosphorylation of signal transducer and activator of transcription (STAT) proteins through the activation of its...

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Bibliografische Detailangaben

Hauptverfasser:	Samir Bolívar, Renatto Anfossi, Claudio Humeres, Raúl Vivar, Pía Boza, Claudia Muñoz, Viviana Pardo-Jimenez, Francisco Olivares-Silva, Guillermo Díaz-Araya
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2018-11-01
Schriftenreihe:	Frontiers in Pharmacology
Schlagworte:	IFN-β (interferon β) cardiac fibroblast STAT proinflammatory anti-infammatory
Online-Zugang:	https://www.frontiersin.org/article/10.3389/fphar.2018.01368/full
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