Transient Receptor Potential Melastatin 7 (TRPM7) Contributes to H2O2-Induced Cardiac Fibrosis via Mediating Ca2+ Influx and Extracellular Signal–Regulated Kinase 1/2 (ERK1/2) Activation in Cardiac Fibroblasts

Abstract.: Transient receptor potential melastatin 7 (TRPM7), a Ca2+-nonselective cation channel, plays a key role in the pathophysiological response of multiple cell types. However, the role of TRPM7 channels in hydrogen peroxide (H2O2)-induced cardiac fibrosis remains unclear. This study aimed to...

Descrizione completa

Dettagli Bibliografici

Autori principali:	Jin-Lei Guo, Yang Yu, Yan-Yan Jia, Yun-Zi Ma, Bo-Yu Zhang, Pei-Qing Liu, Shao-Rui Chen, Jian-Min Jiang
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2014-01-01
Serie:	Journal of Pharmacological Sciences
Accesso online:	http://www.sciencedirect.com/science/article/pii/S1347861319301410
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!