Mesenchymal stem cells alleviate liver injury induced by chronic-binge ethanol feeding in mice via release of TSG6 and suppression of STAT3 activation

Abstract Background Mesenchymal stem cells (MSCs) are a population of pluripotent cells that might be used for treatment of liver disease. However, the efficacy of MSCs for mice with alcoholic hepatitis (AH) and its underlying mechanism remains unclear. Methods MSCs were isolated from the bone marro...

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Ngā kaituhi matua:	Yue-Meng Wan, Zhi-qiang Li, Qiong Zhou, Chang Liu, Men-Jie Wang, Hui-Xin Wu, Yun-Zhen Mu, Yue-Feng He, Yuan Zhang, Xi-Nan Wu, Yu-Hua Li, Zhi-Yuan Xu, Hua-Mei Wu, Ying Xu, Jin-Hui Yang, Xiao-Fang Wang
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	BMC 2020-01-01
Rangatū:	Stem Cell Research & Therapy
Ngā marau:	Alcoholic hepatitis Bone marrow mesenchymal stem cells Oxidative stress Neutrophil infiltration Macrophage infiltration Cytokines
Urunga tuihono:	https://doi.org/10.1186/s13287-019-1547-8
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!