Sevoflurane induces the inattention, cognitive impairment, and motor dysfunction by hypermethylation of retinoic acid receptor α in the medial prefrontal cortex of neonatal mice

Abstract Background: External stimuli during neurodevelopment can alter DNA methylation, affecting gene expression that disrupt brain development. The impact of multiple non‐consecutive sevoflurane (MNS) exposures on DNA methylation patterns and key methylated genes involved in neurodevelopmental to...

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Detalhes bibliográficos

Principais autores:	Yu Hou, Shuai Li, Qi Hou, Runjia Wang, Zhenghao Deng, Xiyuan Xu, Zhichao Li, Linhui Ma, Yuan Shen, Qidong Liu, Hui Zheng
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2025-10-01
coleção:	View
Assuntos:	DNA methylation medial prefrontal cortex multiple non‐consecutive sevoflurane exposures neurodevelopmental toxicity retinoic acid receptor α
Acesso em linha:	https://doi.org/10.1002/VIW.20250072
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