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LRRK2 kinase inhibition protects against Parkinson's disease-associated environmental toxicants

Idiopathic Parkinson's disease (PD) is epidemiologically linked with exposure to toxicants such as pesticides and solvents, which comprise a wide array of chemicals that pollute our environment. While most are structurally distinct, a common cellular target for their toxicity is mitochondrial dysfun...

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主要な著者: Neda M. Ilieva, Eric K. Hoffman, Mohammed A. Ghalib, J. Timothy Greenamyre, Briana R. De Miranda
フォーマット: Artigo
言語:Inglês
出版事項: Elsevier 2024-06-01
シリーズ:Neurobiology of Disease
主題:
オンライン・アクセス:http://www.sciencedirect.com/science/article/pii/S0969996124001219
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