Sirolimus‐ and cyclosporine‐loaded nanostructured lipid carriers: Development, characterization, and in vitro evaluation in T‐cell profiles of patients with a history of recurrent pregnancy loss

Abstract Purpose The authors developed nanostructured lipid carriers (NLCs) loaded with sirolimus (SRL) and cyclosporine (CsA) to improve their therapeutic efficacy in recurrent pregnancy loss (RPL) patients. Methods Mono‐delivery and co‐delivery of SRL and CsA by NLCs (S‐NLCs, C‐NLCs, and S‐C‐NLCs)...

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Autors principals:	Forough Parhizkar, Mehdi Yousefi, Mohammad Sadegh Soltani‐Zangbar, Zahra Parhizkar, Leili Aghebati‐Maleki, Soheil Abbaspour‐Ravasjani, Roza Motavalli, Amin Alizadegan, Maryam Mojahedi, Sina Baharaghdam, Amin Kamrani, Shahla Danaii, Mehdi Talebi, Farhad Jadidi‐Niaragh, Hamed Hamishehkar, Hossein Samadi Kafil, Ata Mahmoodpoor, Javad Ahmadian Heris
Format:	Artigo
Idioma:	Inglês
Publicat:	Wiley 2023-01-01
Col·lecció:	Reproductive Medicine and Biology
Matèries:	cyclosporine nanostructured lipid carriers recurrent pregnancy loss sirolimus
Accés en línia:	https://doi.org/10.1002/rmb2.12509
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