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Case Report: Neoadjuvant chemoimmunotherapy achieving pathological complete response in two cases of stage III EGFR-mutant NSCLC with high PD-L1 expression

Resectable locally advanced EGFR-mutant non-small cell lung cancer (NSCLC) represents a distinct therapeutic challenge. Owing to an inherently immunosuppressive tumor microenvironment—frequently characterized by absence of or low PD-L1 expression and sparse CD8+ tumor-infiltrating lymphocytes—patien...

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Hlavní autoři: Diming Wang, Tangbin Liu, Jian Zhao, Bowen Ding, Yongliang Niu
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2026-06-01
Edice:Frontiers in Oncology
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On-line přístup:https://www.frontiersin.org/articles/10.3389/fonc.2026.1844982/full
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