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Janus Kinase Inhibitors in the Treatment of Vitiligo: A Review

Vitiligo is a multifactorial reversible skin disorder characterized by distinct white patches that result from melanocyte destruction. Activated CXCR3+ CD8+ T cells promote melanocyte detachment and apoptosis through interferon-gamma (IFN-γ secretion and chemokines secreted by keratinocytes through...

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Principais autores: Fei Qi, Fang Liu, Ling Gao
פורמט: Artigo
שפה:Inglês
יצא לאור: Frontiers Media S.A. 2021-11-01
סדרה:Frontiers in Immunology
נושאים:
vitiligo
JAK/STAT-1 signaling pathway
JAK inhibitors
chemokines
IFN - interferon
גישה מקוונת:https://www.frontiersin.org/articles/10.3389/fimmu.2021.790125/full
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