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Specific features of human monocytes activation by monophosphoryl lipid A

Abstract We deciphered the mechanisms of production of pro- and anti-inflammatory cytokines by adherent human blood mononuclear cells (PBMC) activated by lipopolysaccharide (LPS) or monophosphoryl lipid A (MPLA). Both LPS and MPLA induced tumor necrosis factor (TNF) production proved to be dependent...

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Autors principals: Ryme Chentouh, Catherine Fitting, Jean-Marc Cavaillon
Format: Artigo
Idioma:Inglês
Publicat: Nature Portfolio 2018-05-01
Col·lecció:Scientific Reports
Accés en línia:https://doi.org/10.1038/s41598-018-25367-y
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