Association between the extent of intrapulmonary spread on chest CT and false-negative results of T-SPOT.TB in pulmonary tuberculosis: a retrospective study

Abstract Background The T-SPOT.TB assay is widely used for the adjunctive diagnosis of tuberculosis (TB). However, clinicians often encounter false-negative T-SPOT.TB results. The extent of TB spread may influence host immune functions, which can influence the results of the T-SPOT.TB test. However,...

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Autors principals:	Ryo Sato, Naoki Takasaka, Yusuke Hosaka, Taiki Fukuda, Kyota Shinfuku, Makiko Takatsuka, Tsukasa Hasegawa, Masami Yamada, Yumie Yamanaka, Kai Ryu, Takeo Ishikawa, Jun Araya
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2025-03-01
Col·lecció:	BMC Infectious Diseases
Matèries:	Pulmonary tuberculosis T-SPOT.TB Chest CT Interferon-gamma release assay
Accés en línia:	https://doi.org/10.1186/s12879-025-10777-x
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