Genetic signatures in the envelope glycoproteins of HIV-1 that associate with broadly neutralizing antibodies.

A steady increase in knowledge of the molecular and antigenic structure of the gp120 and gp41 HIV-1 envelope glycoproteins (Env) is yielding important new insights for vaccine design, but it has been difficult to translate this information to an immunogen that elicits broadly neutralizing antibodies...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	S Gnanakaran, Marcus G Daniels, Tanmoy Bhattacharya, Alan S Lapedes, Anurag Sethi, Ming Li, Haili Tang, Kelli Greene, Hongmei Gao, Barton F Haynes, Myron S Cohen, George M Shaw, Michael S Seaman, Amit Kumar, Feng Gao, David C Montefiori, Bette Korber
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Public Library of Science (PLoS) 2010-01-01
Schriftenreihe:	PLoS Computational Biology
Online-Zugang:	http://europepmc.org/articles/PMC2951345?pdf=render
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