Brachyury promotes proliferation and migration of colorectal cancer cells by targeting MMP14

Abstract Background The incidence and mortality rates of colorectal cancer (CRC) are rising, and it is the second most common cause of cancer-related deaths worldwide. Although the transcription factor, Brachyury is intricately linked with various clinical malignancies, the mechanisms by which it in...

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Detalhes bibliográficos

Principais autores:	Ming Chen, Huiheng Qu, Xiao Liang, Ying Huang, Zhengjie Yang, Pei Lu, Keqin Shi, Peng Chen, Yanjing Zhang, Hui Zhou, Jiazeng Xia, Jun Shen
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2025-04-01
coleção:	Cancer Cell International
Assuntos:	Brachyury Colorectal cancer MMP14 Proliferation Migration
Acesso em linha:	https://doi.org/10.1186/s12935-025-03726-w
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